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        <div class="me-2"><a class="text-gray" data-turbo-frame="_top" href="/en/stock/Adagene-Inc-ADR-US0053291078">Adagene Inc - ADR</a></div>
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      <a target="_blank" rel="nofollow" href="https://www.globenewswire.com/news-release/2026/04/02/3267231/0/en/Adagene-Announces-Clinical-Collaboration-with-Incyte-to-Evaluate-Muzastotug-ADG126-in-Combination-with-Incyte-s-TGF%C3%9FR2xPD-1-Bispecific-Antibody-INCA33890-in-Patients-with-Microsate.html">Adagene Announces Clinical Collaboration with Incyte to Evaluate Muzastotug (ADG126) in Combination with Incyte&#39;s TGFßR2xPD-1 Bispecific Antibody (INCA33890) in Patients with Microsatellite Stable Colorectal Cancer (MSS CRC)</a>
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        Phase 1 study of INCA33890 and muzastotug expected to begin in 2026 in 3L MSS CRC patients with and without liver metastases
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        <div class="me-2"><a class="text-gray" data-turbo-frame="_top" href="/en/stock/Adagene-Inc-ADR-US0053291078">Adagene Inc - ADR</a></div>
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        <div class="me-2 text-gray">6 months ago</div>
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      <a target="_blank" rel="nofollow" href="https://www.globenewswire.com/news-release/2026/04/02/3267222/0/en/Updated-Data-from-Phase-1b-2-Study-of-Muzastotug-in-Combination-with-KEYTRUDA-pembrolizumab-in-Late-line-Patients-with-Microsatellite-Stable-Colorectal-Cancer-Demonstrate-Improved-.html">Updated Data from Phase 1b/2 Study of Muzastotug in Combination with KEYTRUDA® (pembrolizumab) in Late-line Patients with Microsatellite Stable Colorectal Cancer Demonstrate Improved Durability of Response</a>
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        Dose-Dependent Efficacy Results : As of the latest data cut, muzastotug achieved a 31% (8/26) confirmed overall response rate (ORR) in the combined 20 mg/kg dose cohorts, showing a clear improvement over the 13% ORR (5/39) in the combined 10 mg/kg dose cohorts
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        <div class="me-2"><a class="text-gray" data-turbo-frame="_top" href="/en/stock/Adagene-Inc-ADR-US0053291078">Adagene Inc - ADR</a></div>
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        <div class="me-2 text-gray">GlobeNewsWire</div>
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        <div class="me-2 text-gray">6 months ago</div>
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      <a target="_blank" rel="nofollow" href="https://www.globenewswire.com/news-release/2026/04/01/3267038/0/en/Adagene-Reports-Full-Year-2025-Financial-Results-and-Provides-Corporate-Update.html">Adagene Reports Full Year 2025 Financial Results and Provides Corporate Update</a>
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        In 2025, muzastotug showed 29% confirmed overall response rate (ORR) among 21 patients with MSS CRC in the 20 mg/kg dose cohorts Median overall survival (OS) for the 10 mg/kg cohorts was 19.4 months, with a median follow-up of 17.8 months  4% overall discontinuation rate, no dose limiting toxicities, and no Grade 4 or 5 treatment-related adverse events (TRAEs) across 67 patients in all dose coh...
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