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        <div class="me-2"><a class="text-gray" data-turbo-frame="_top" href="/en/stock/Aeglea-BioTherapeutics-Inc-US00773J1034">Aeglea BioTherapeutics Inc</a></div>
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      <a target="_blank" rel="nofollow" href="https://www.globenewswire.com/news-release/2026/04/16/3275826/0/en/Spyre-Therapeutics-Inc-Announces-Closing-of-Public-Offering-and-Full-Exercise-of-the-Underwriters-Option-to-Purchase-Additional-Shares-for-Gross-Proceeds-of-463-5-Million.html">Spyre Therapeutics, Inc. Announces Closing of Public Offering and Full Exercise of the Underwriters&#39; Option to Purchase Additional Shares for Gross Proceeds of $463.5 Million</a>
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        WALTHAM, Mass., April 16, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (“Spyre” or the “Company”) (Nasdaq: SYRE), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (IBD) and rheumatic diseases, today announced the closing of its previously announced underwritten public offering ...
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      <a target="_blank" rel="nofollow" href="https://www.globenewswire.com/news-release/2026/04/15/3274098/0/en/Spyre-Therapeutics-Announces-Pricing-of-Upsized-403-0-Million-Public-Offering-of-Common-Stock.html">Spyre Therapeutics Announces Pricing of Upsized $403.0 Million Public Offering of Common Stock</a>
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        WALTHAM, Mass., April 14, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (“Spyre” or the “Company”) (Nasdaq: SYRE), a clinical-stage biotechnology company advancing best-in-class antibody engineering, dose optimization, and rational therapeutic combinations for the treatment of Inflammatory Bowel Disease (“IBD”) and other immune-mediated diseases, today announced the pricing of its previousl...
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      <a target="_blank" rel="nofollow" href="https://www.globenewswire.com/news-release/2026/04/13/3272916/0/en/Spyre-Therapeutics-Announces-Proposed-Public-Offering-of-its-Common-Stock.html">Spyre Therapeutics Announces Proposed Public Offering of its Common Stock</a>
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        WALTHAM, Mass., April 13, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (“Spyre” or the “Company”) (Nasdaq: SYRE), a clinical-stage biotechnology company advancing best-in-class antibody engineering, dose optimization, and rational therapeutic combinations for the treatment of Inflammatory Bowel Disease (“IBD”) and other immune-mediated diseases, today announced that it has commenced an und...
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        <div class="me-2"><a class="text-gray" data-turbo-frame="_top" href="/en/stock/Aeglea-BioTherapeutics-Inc-US00773J1034">Aeglea BioTherapeutics Inc</a></div>
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      <a target="_blank" rel="nofollow" href="https://www.investors.com/news/technology/spyre-therapeutics-stock-ulcerative-colitis-takeda-pharmaceutical-entyvio/">Spyre Therapeutics Flies On Takeda-Rivaling Ulcerative Colitis Results</a>
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        Spyre Therapeutics stock soared to a four-year high Monday on positive 12-week test results for its ulcerative colitis treatment.
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      <a target="_blank" rel="nofollow" href="https://www.globenewswire.com/news-release/2026/04/13/3272353/0/en/Spyre-Announces-Potential-Best-in-Class-SPY001-Part-A-Induction-Results-from-SKYLINE-Trial-in-Moderate-to-Severe-Ulcerative-Colitis-Patients.html">Spyre Announces Potential Best-in-Class SPY001 Part A Induction Results from SKYLINE Trial in Moderate-to-Severe Ulcerative Colitis Patients</a>
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        SPY001 met its primary endpoint with a  statistically significant reduction of 9.2 points (p
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      <a target="_blank" rel="nofollow" href="https://www.globenewswire.com/news-release/2026/04/10/3272032/0/en/Spyre-Therapeutics-to-Host-Conference-Call-to-Report-SPY001-Part-A-Induction-Topline-Results-from-SKYLINE-Trial-in-Moderate-to-Severe-Ulcerative-Colitis-Patients-on-April-13-2026.html">Spyre Therapeutics to Host Conference Call to Report SPY001 Part A Induction Topline Results from SKYLINE Trial in Moderate-to-Severe Ulcerative Colitis Patients on April 13, 2026</a>
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        WALTHAM, Mass., April 10, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (IBD) and rheumatic diseases, today announced it will report SPY001 Part A induction topline results from the SKYLINE trial in moderate-to-sev...
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        <div class="me-2"><a class="text-gray" data-turbo-frame="_top" href="/en/stock/Aeglea-BioTherapeutics-Inc-US00773J1034">Aeglea BioTherapeutics Inc</a></div>
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      <a target="_blank" rel="nofollow" href="https://www.fool.com/coverage/filings/2026/04/08/spyre-ceo-sells-usd740k-in-stock-after-300-surge-as-key-q3-data-nears/">Spyre CEO Sells $740K in Stock After 300% Surge as Key Q3 Data Nears</a>
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        The CEO of Spyre Therapeutics reported selling 15,000 shares for a total transaction value of about $740,000 on April 1, 2026. The transaction represented 2.33% of Cameron Turtle&#39;s directly held common stock holdings and reduced direct ownership to 627,540 common shares post-sale, as reported in the Form 4.
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      <a target="_blank" rel="nofollow" href="https://www.globenewswire.com/news-release/2026/04/03/3268133/0/en/Spyre-Therapeutics-Announces-Grants-of-Inducement-Awards.html">Spyre Therapeutics Announces Grants of Inducement Awards</a>
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        WALTHAM, Mass., April 03, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease and rheumatic diseases, today announced that Spyre&#39;s independent Compensation Committee of the Board of Directors a...
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