$8.04
3.71% today
Nasdaq, Feb 28, 05:06 pm CET
ISIN
US48576U1060
Symbol
KPTI
Sector
Industry

Karyopharm Therapeutics, Inc. Stock price

$8.35
-1.94 18.85% 1M
-3.65 30.42% 6M
-1.79 17.69% YTD
-12.80 60.52% 1Y
-146.60 94.61% 3Y
-222.35 96.38% 5Y
-400.55 97.96% 10Y
Nasdaq, Closing price Thu, Feb 27 2025
-1.48 15.06%
ISIN
US48576U1060
Symbol
KPTI
Sector
Industry

Key metrics

Market capitalization $70.27m
Enterprise Value $156.05m
P/E (TTM) P/E ratio negative
EV/FCF (TTM) EV/FCF negative
EV/Sales (TTM) EV/Sales 1.07
P/S ratio (TTM) P/S ratio 0.48
P/B ratio (TTM) P/B ratio negative
Revenue growth (TTM) Revenue growth -0.55%
Revenue (TTM) Revenue $145.24m
EBIT (operating result TTM) EBIT $-119.44m
Free Cash Flow (TTM) Free Cash Flow $-127.63m
Cash position $108.74m
EPS (TTM) EPS $-15.34
P/E forward negative
P/S forward 0.47
EV/Sales forward 1.05
Short interest 16.59%
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Karyopharm Therapeutics, Inc. Stock Analysis

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Analyst Opinions

7 Analysts have issued a Karyopharm Therapeutics, Inc. forecast:

6x Buy
86%
1x Hold
14%

Analyst Opinions

7 Analysts have issued a Karyopharm Therapeutics, Inc. forecast:

Buy
86%
Hold
14%

Financial data from Karyopharm Therapeutics, Inc.

Income Statement P&L | Balance Sheet | Cash Flow


Quarter TTM Annually
Dec '24
+/-
%
145 145
1% 1%
100%
- Direct Costs 6.35 6.35
16% 16%
4%
139 139
1% 1%
96%
- Selling and Administrative Expenses 115 115
12% 12%
79%
- Research and Development Expense 143 143
3% 3%
98%
-119 -119
8% 8%
-82%
- Depreciation and Amortization 0.34 0.34
36% 36%
0%
EBIT (Operating Income) EBIT -119 -119
8% 8%
-82%
Net Profit -76 -76
47% 47%
-53%

In millions USD.

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Karyopharm Therapeutics, Inc. Stock News

Neutral
PRNewsWire
4 days ago
NEWTON, Mass. , Feb. 24, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that it will implement a 1-for-15 reverse stock split of the issued shares of the Company's common stock ("Reverse Stock Split"), effective at 5:00 p.m.
Neutral
Seeking Alpha
9 days ago
Karyopharm Therapeutics Inc. (NASDAQ:KPTI ) Q4 2024 Earnings Call February 19, 2025 8:00 AM ET Company Participants Brendan Strong - SVP, IR Richard Paulson - President and CEO Reshma Rangwala - CMO & Head of Research Sohanya Cheng - CCO & Head of Business Development Lori Macomber - EVP, CFO, & Treasurer Conference Call Participants Colleen Kusy - Baird Maury Raycroft - Jefferies Unidentified ...
Neutral
PRNewsWire
9 days ago
– Total Revenue of $145 Million and U.S. XPOVIO® (selinexor) Net Product Revenue of $113 Million for Full Year 2024 – – Top-Line Data Readout from Phase 3 SENTRY Trial Evaluating Selinexor in Combination with Ruxolitinib in Patients with JAKi-Naïve Myelofibrosis Anticipated in 2H 2025; Company on Track to Complete Enrollment in 1H 2025 – – Company Announces Update to Phase 3 XPORT-EC-042 Trial ...
More Karyopharm Therapeutics, Inc. News

Company Profile

Karyopharm Therapeutics, Inc. is an oncology-focused pharmaceutical company dedicated to the discovery, development, and commercialization of novel first-in-class drugs directed against nuclear export and related targets for the treatment of cancer and other major diseases. Its SINE compounds function by binding with and inhibiting the nuclear export protein XPO1 (or CRM1). Karyopharm's lead compound, XPOVIOTM (selinexor), received accelerated approval from the FDA in combination with dexamethasone as a treatment for patients with heavily pretreated multiple myeloma. A Marketing Authorization Application for selinexor is also currently under review by the European Medicines Agency (EMA). In addition to single-agent and combination activity against a variety of human cancers, SINE compounds have also shown biological activity in models of neurodegeneration, inflammation, autoimmune disease, certain viruses and wound-healing. Karyopharm has several investigational programs in clinical or preclinical development. The company was founded by Joseph Araujo, Ronald A. DePinho, Pamela A Silver, Giulio Draetta, Michael G. Kauffman and Sharon Shacham on December 22, 2008 and is headquartered in Newton, MA.

Head office United States
CEO Richard Paulson
Employees 279
Founded 2008
Website www.karyopharm.com

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