$1.62
6.36%
Nasdaq, Sep 25, 04:00 pm EDT. Closed.
ISIN
US48576U1060
Symbol
KPTI

Karyopharm Therapeutics, Inc. Target price 2026 - Analyst rating & recommendation

Karyopharm Therapeutics, Inc. Classifications & Recommendation

Buy
82%
Hold
18%

Karyopharm Therapeutics, Inc. Price Target

Target Price $7.65
Price $1.62
Potential
Number of Estimates 6
6 Analysts have issued a price target Karyopharm Therapeutics, Inc. 2027 . The average Karyopharm Therapeutics, Inc. target price is $7.65. This is higher than the current stock price. The highest price target is , the lowest is .
A rating was issued by 11 analysts: 9 Analysts recommend Karyopharm Therapeutics, Inc. to buy, 2 to hold and 0 to sell.
Analysts don't have a crystal ball either, but they do represent the opinion of the market quite well. You should not take the price potential and the ratings as a recommendation to act. Rather, they serve as an additional building block for your own opinion or stock analysis.
Analyst Estimates: Analysts believe that the Karyopharm Therapeutics, Inc. stock has an average upside potential 2027 of . Most analysts recommend the Karyopharm Therapeutics, Inc. stock at Purchase.

Sales and Margin forecast 2026, 2027 to 2033

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Select at least one metric to display the chart.


Quarter Annually
Dec '25 2026
Estimates
Revenue Million $ 146.07 136.08
0.57% 6.84%
Net Margin -134.21% -73.71%
155.07% 45.08%

7 Analysts have issued a sales forecast Karyopharm Therapeutics, Inc. 2026 . The average Karyopharm Therapeutics, Inc. sales estimate is

$136m
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. This is
7.19% lower
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than the revenue of the last 12 months(TTM). The highest sales forecast is
$145m 1.37%
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, the lowest is
$121m 17.26%
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.

This results in the following potential growth metrics:

Revenue Estimates

2025 $146m 0.57%
2026
$136m 6.84%
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2027
$174m 27.72%
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2028
$214m 23.22%
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2029
$348m 62.61%
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2030
$344m 1.17%
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2031
$422m 22.51%
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2032
$496m 17.74%
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2033
$433m 12.82%
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7 Karyopharm Therapeutics, Inc. Analysts have issued a net profit forecast 2026. The average Karyopharm Therapeutics, Inc. net profit estimate is

$-100m
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. This is
55.37% higher
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than the net profit for the last 12 months(TTM). The highest net profit forecast is
$-65.3m 70.97%
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, the lowest is
$-134m 40.56%
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.

This results in the following potential growth metrics and future Net Margins:

Net Profit Estimates

2025 $-196m 156.53%
2026
$-100m 48.83%
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2027
$-53.5m 46.67%
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2028
$-75.5m 41.10%
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2029
$21.5m 128.49%
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2030
$37.9m 76.38%
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2031
$50.4m 32.92%
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2032
$59.0m 16.97%
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2033
$66.4m 12.54%
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Net Margin

2025 -134.21% 155.07%
2026
-73.71% 45.08%
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2027
-30.78% 58.24%
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2028
-35.25% 14.52%
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2029
6.18% 117.53%
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2030
11.02% 78.32%
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2031
11.96% 8.53%
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2032
11.88% 0.67%
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2033
15.34% 29.12%
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Earnings per share, P/E ratio and EV/sales Estimates 2026, 2027 to 2033

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Select at least one metric to display the chart.


Quarter Annually
Dec '25 2026
Estimates
Earnings Per Share $ -17.93 -4.42
90.54% 75.35%
P/E negative
EV/Sales 2.16

7 Analysts have issued a Karyopharm Therapeutics, Inc. forecast for earnings per share. The average Karyopharm Therapeutics, Inc. EPS is

$-4.42
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. This is
43.04% higher
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than earnings per share in the financial year 2025. The highest EPS forecast is
$-2.88 62.89%
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, the lowest is
$-5.89 24.10%
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.

This results in the following potential growth metrics and future valuations:

Earnings Per Share

2025 $-17.93 90.54%
2026
$-4.42 75.35%
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2027
$-2.36 46.61%
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2028
$-3.33 41.10%
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2029
$0.95 128.53%
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2030
$1.67 75.79%
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2031
$2.22 32.93%
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2032
$2.60 17.12%
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2033
$2.93 12.69%
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P/E ratio

Current -0.21 44.69%
2026
-0.37 77.20%
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2027
-0.69 86.49%
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2028
-0.49 28.99%
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2029
1.71 448.98%
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2030
0.97 43.27%
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2031
0.73 24.74%
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2032
0.62 15.07%
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2033
0.55 11.29%
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Based on analysts' sales estimates for 2026, the Karyopharm Therapeutics, Inc. stock is valued at an EV/Sales of

and an P/S ratio of .

This results in the following potential growth metrics and future valuations:

EV/Sales

Current 2.00 9.29%
2026
2.16 7.99%
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2027
1.69 21.70%
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2028
1.37 18.85%
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2029
0.84 38.50%
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2030
0.85 1.18%
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2031
0.70 18.37%
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2032
0.59 15.06%
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2033
0.68 14.71%
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P/S ratio

Current 0.25 26.66%
2026
0.27 7.74%
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2027
0.21 21.70%
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2028
0.17 18.83%
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2029
0.11 38.52%
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2030
0.11 1.23%
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2031
0.09 18.45%
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2032
0.07 15.04%
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2033
0.08 14.73%
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Current Karyopharm Therapeutics, Inc. Upgrades & Downgrades

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Analyst Rating Action Date
HC Wainwright & Co.
Locked
➜
Locked
Locked Jul 31 2026
Piper Sandler
Locked
➜
Locked
Locked Jul 31 2026
HC Wainwright & Co.
Locked
➜
Locked
Locked May 06 2026
Piper Sandler
Locked
➜
Locked
Locked Apr 27 2026
Piper Sandler
Locked
➜
Locked
Locked Mar 30 2026
Baird
Locked
➜
Locked
Locked Mar 25 2026
HC Wainwright & Co.
Locked
➜
Locked
Locked Mar 25 2026
Analyst Rating Date
Locked
HC Wainwright & Co.:
Locked
➜
Locked
Jul 31 2026
Locked
Piper Sandler:
Locked
➜
Locked
Jul 31 2026
Locked
HC Wainwright & Co.:
Locked
➜
Locked
May 06 2026
Locked
Piper Sandler:
Locked
➜
Locked
Apr 27 2026
Locked
Piper Sandler:
Locked
➜
Locked
Mar 30 2026
Locked
Baird:
Locked
➜
Locked
Mar 25 2026
Locked
HC Wainwright & Co.:
Locked
➜
Locked
Mar 25 2026

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