$69.15
1.10% day before yesterday
Nasdaq, Oct 03, 10:12 pm CET
ISIN
US4622221004
Symbol
IONS

Ionis Pharmaceuticals, Inc. Target price 2025 - Analyst rating & recommendation

Ionis Pharmaceuticals, Inc. Classifications & Recommendation:

Buy
74%
Hold
26%

Ionis Pharmaceuticals, Inc. Price Target

Target Price $71.40
Price $69.15
Potential
Number of Estimates 27
27 Analysts have issued a price target Ionis Pharmaceuticals, Inc. 2026 . The average Ionis Pharmaceuticals, Inc. target price is $71.40. This is higher than the current stock price. The highest price target is , the lowest is .
A rating was issued by 31 analysts: 23 Analysts recommend Ionis Pharmaceuticals, Inc. to buy, 8 to hold and 0 to sell.
Analysts don't have a crystal ball either, but they do represent the opinion of the market quite well. You should not take the price potential and the ratings as a recommendation to act. Rather, they serve as an additional building block for your own opinion or stock analysis.
Analyst Estimates: Analysts believe that the Ionis Pharmaceuticals, Inc. stock has an average upside potential 2026 of . Most analysts recommend the Ionis Pharmaceuticals, Inc. stock at Purchase.

Sales and Margin forecast 2025, 2026 to 2032

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Quarter Annually
Dec '24 2025
Estimates
Revenue Million $ 705.14 876.48
10.48% 24.30%
EBITDA Margin -65.68% -42.55%
61.22% 35.22%
Net Margin -64.37% -47.22%
38.42% 26.64%

29 Analysts have issued a sales forecast Ionis Pharmaceuticals, Inc. 2025 . The average Ionis Pharmaceuticals, Inc. sales estimate is

$876m
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. This is
7.16% lower
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than the revenue of the last 12 months(TTM). The highest sales forecast is
$1.0b 5.93%
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, the lowest is
$818m 13.38%
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.

This results in the following potential growth metrics:

Revenue Estimates

2024 $705m 10.48%
2025
$876m 24.30%
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2026
$933m 6.50%
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2027
$1.3b 39.59%
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2028
$1.7b 29.16%
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2029
$2.3b 36.01%
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2030
$2.9b 28.75%
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2031
$3.3b 12.28%
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2032
$3.8b 14.78%
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12 Analysts have issued an Ionis Pharmaceuticals, Inc. EBITDA forecast 2025. The average Ionis Pharmaceuticals, Inc. EBITDA estimate is

$-373m
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. This is
43.35% lower
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than the EBITDA of the last 12 months(TTM). The highest EBITDA forecast is
$-293m 12.50%
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, the lowest is
$-407m 56.59%
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.

This results in the following potential growth metrics and future EBITDA Margins:

EBITDA Estimates

2024 $-463m 44.33%
2025
$-373m 19.48%
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2026
$-508m 36.24%
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2027
$-280m 44.88%
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EBITDA Margin

2024 -65.68% 61.22%
2025
-42.55% 35.22%
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2026
-54.43% 27.92%
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2027
-21.49% 60.52%
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29 Ionis Pharmaceuticals, Inc. Analysts have issued a net profit forecast 2025. The average Ionis Pharmaceuticals, Inc. net profit estimate is

$-414m
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. This is
54.29% lower
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than the net profit for the last 12 months(TTM). The highest net profit forecast is
$-264m 1.53%
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, the lowest is
$-449m 67.52%
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.

This results in the following potential growth metrics and future Net Margins:

Net Profit Estimates

2024 $-454m 23.92%
2025
$-414m 8.83%
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2026
$-516m 24.68%
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2027
$-274m 46.97%
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2028
$206m 175.27%
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2029
$567m 175.17%
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2030
$911m 60.82%
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2031
$1.0b 12.66%
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2032
$1.3b 21.98%
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Net Margin

2024 -64.37% 38.42%
2025
-47.22% 26.64%
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2026
-55.28% 17.07%
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2027
-21.00% 62.01%
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2028
12.24% 158.29%
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2029
24.76% 102.29%
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2030
30.93% 24.92%
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2031
31.03% 0.32%
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2032
32.98% 6.28%
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Earnings per share, P/E ratio and EV/sales Estimates 2025, 2026 to 2032

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Quarter Annually
Dec '24 2025
Estimates
Earnings Per Share $ -3.04 -2.60
18.75% 14.47%
P/E negative
EV/Sales 11.40

29 Analysts have issued a Ionis Pharmaceuticals, Inc. forecast for earnings per share. The average Ionis Pharmaceuticals, Inc. EPS is

$-2.60
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. This is
76.87% lower
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than earnings per share in the financial year 2024. The highest EPS forecast is
$-1.66 12.93%
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, the lowest is
$-2.82 91.84%
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.

This results in the following potential growth metrics and future valuations:

Earnings Per Share

2024 $-3.04 18.75%
2025
$-2.60 14.47%
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2026
$-3.24 24.62%
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2027
$-1.72 46.91%
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2028
$1.29 175.00%
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2029
$3.56 175.97%
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2030
$5.72 60.67%
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2031
$6.45 12.76%
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2032
$7.87 22.02%
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P/E ratio

Current -47.04 187.89%
2025
-26.60 43.45%
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2026
-21.33 19.81%
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2027
-40.23 88.61%
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2028
53.45 232.86%
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2029
19.43 63.65%
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2030
12.08 37.83%
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2031
10.72 11.26%
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2032
8.79 18.00%
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Based on analysts' sales estimates for 2025, the Ionis Pharmaceuticals, Inc. stock is valued at an EV/Sales of

11.40
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and an P/S ratio of
12.58
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.

This results in the following potential growth metrics and future valuations:

EV/Sales

Current 10.58 52.89%
2025
11.40 7.70%
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2026
10.70 6.10%
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2027
7.67 28.36%
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2028
5.93 22.58%
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2029
4.36 26.47%
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2030
3.39 22.33%
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2031
3.02 10.94%
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2032
2.63 12.87%
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P/S ratio

Current 11.68 47.59%
2025
12.58 7.71%
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2026
11.81 6.10%
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2027
8.46 28.36%
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2028
6.55 22.58%
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2029
4.82 26.47%
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2030
3.74 22.33%
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2031
3.33 10.94%
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2032
2.90 12.88%
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Current Ionis Pharmaceuticals, Inc. Upgrades & Downgrades

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Analyst Rating Action Date
Goldman Sachs
Locked
Locked
Locked Sep 26 2025
B of A Securities
Locked
Locked
Locked Sep 23 2025
HC Wainwright & Co.
Locked
Locked
Locked Sep 23 2025
Guggenheim
Locked
Locked
Locked Sep 23 2025
Morgan Stanley
Locked
Locked
Locked Sep 23 2025
Barclays
Locked
Locked
Locked Sep 23 2025
RBC Capital
Locked
Locked
Locked Sep 04 2025
Analyst Rating Date
Locked
Goldman Sachs:
Locked
Locked
Sep 26 2025
Locked
B of A Securities:
Locked
Locked
Sep 23 2025
Locked
HC Wainwright & Co.:
Locked
Locked
Sep 23 2025
Locked
Guggenheim:
Locked
Locked
Sep 23 2025
Locked
Morgan Stanley:
Locked
Locked
Sep 23 2025
Locked
Barclays:
Locked
Locked
Sep 23 2025
Locked
RBC Capital:
Locked
Locked
Sep 04 2025

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