$34.47
1.29% yesterday
Nasdaq, May 20, 10:13 pm CET
ISIN
US4622221004
Symbol
IONS
Sector
Industry

Ionis Pharmaceuticals, Inc. Target price 2025 - Analyst rating & recommendation

Ionis Pharmaceuticals, Inc. Classifications & Recommendation:

Buy
68%
Hold
29%
Sell
4%

Ionis Pharmaceuticals, Inc. Price Target

Target Price $56.25
Price $34.47
Potential
Number of Estimates 24
24 Analysts have issued a price target Ionis Pharmaceuticals, Inc. 2026 . The average Ionis Pharmaceuticals, Inc. target price is $56.25. This is higher than the current stock price. The highest price target is , the lowest is .
A rating was issued by 28 analysts: 19 Analysts recommend Ionis Pharmaceuticals, Inc. to buy, 8 to hold and 1 to sell.
Analysts don't have a crystal ball either, but they do represent the opinion of the market quite well. You should not take the price potential and the ratings as a recommendation to act. Rather, they serve as an additional building block for your own opinion or stock analysis.
Analyst Estimates: Analysts believe that the Ionis Pharmaceuticals, Inc. stock has an average upside potential 2026 of . Most analysts recommend the Ionis Pharmaceuticals, Inc. stock at Purchase.

Sales and Margin forecast 2025, 2026 to 2029

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Quarter Annually
Dec '24 2025
Estimates
Revenue Million $ 705.14 728.40
10.48% 3.30%
EBITDA Margin -64.26% -68.68%
62.62% 6.89%
Net Margin -68.57% -70.71%
32.65% 3.13%

23 Analysts have issued a sales forecast Ionis Pharmaceuticals, Inc. 2025 . The average Ionis Pharmaceuticals, Inc. sales estimate is

$728m
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. This is
1.49% higher
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than the revenue of the last 12 months(TTM). The highest sales forecast is
$801m 11.61%
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, the lowest is
$615m 14.36%
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.

This results in the following potential growth metrics:

Revenue Estimates

2024 $705m 10.48%
2025
$728m 3.30%
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2026
$877m 20.44%
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2027
$1.2b 37.24%
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2028
$1.6b 35.77%
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2029
$2.2b 35.20%
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8 Analysts have issued an Ionis Pharmaceuticals, Inc. EBITDA forecast 2025. The average Ionis Pharmaceuticals, Inc. EBITDA estimate is

$-500m
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. This is
11.20% lower
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than the EBITDA of the last 12 months(TTM). The highest EBITDA forecast is
$-356m 20.89%
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, the lowest is
$-640m 42.23%
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.

This results in the following potential growth metrics and future EBITDA Margins:

EBITDA Estimates

2024 $-453m 45.58%
2025
$-500m 10.40%
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2026
$-443m 11.35%
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2027
$-193m 56.57%
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2028
$162m 183.86%
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EBITDA Margin

2024 -64.26% 62.62%
2025
-68.68% 6.89%
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2026
-50.55% 26.40%
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2027
-16.00% 68.35%
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2028
9.88% 161.75%
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22 Ionis Pharmaceuticals, Inc. Analysts have issued a net profit forecast 2025. The average Ionis Pharmaceuticals, Inc. net profit estimate is

$-515m
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. This is
8.67% lower
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than the net profit for the last 12 months(TTM). The highest net profit forecast is
$-367m 22.48%
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, the lowest is
$-669m 41.15%
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.

This results in the following potential growth metrics and future Net Margins:

Net Profit Estimates

2024 $-483m 18.75%
2025
$-515m 6.52%
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2026
$-489m 5.05%
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2027
$-227m 53.61%
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2028
$35.2m 115.51%
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2029
$435m 1,135.99%
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Net Margin

2024 -68.57% 32.65%
2025
-70.71% 3.13%
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2026
-55.74% 21.17%
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2027
-18.84% 66.20%
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2028
2.15% 111.41%
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2029
19.67% 814.88%
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Earnings per share, P/E ratio and EV/sales Estimates 2025, 2026 to 2029

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Quarter Annually
Dec '24 2025
Estimates
Earnings Per Share $ -3.04 -3.24
18.75% 6.58%
P/E negative
EV/Sales 7.27

22 Analysts have issued a Ionis Pharmaceuticals, Inc. forecast for earnings per share. The average Ionis Pharmaceuticals, Inc. EPS is

$-3.24
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. This is
8.72% lower
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than earnings per share in the financial year 2024. The highest EPS forecast is
$-2.31 22.48%
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, the lowest is
$-4.21 41.28%
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.

This results in the following potential growth metrics and future valuations:

Earnings Per Share

2024 $-3.04 18.75%
2025
$-3.24 6.58%
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2026
$-3.07 5.25%
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2027
$-1.43 53.42%
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2028
$0.22 115.38%
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2029
$2.73 1,140.91%
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P/E ratio

Current -11.55 17.38%
2025
-10.64 7.88%
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2026
-11.21 5.36%
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2027
-24.17 115.61%
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2028
155.83 744.72%
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2029
12.61 91.91%
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Based on analysts' sales estimates for 2025, the Ionis Pharmaceuticals, Inc. stock is valued at an EV/Sales of

and an P/S ratio of .

This results in the following potential growth metrics and future valuations:

EV/Sales

Current 7.38 10.15%
2025
7.27 1.48%
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2026
6.04 16.97%
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2027
4.40 27.14%
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2028
3.24 26.34%
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2029
2.40 26.04%
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P/S ratio

Current 7.64 9.08%
2025
7.53 1.47%
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2026
6.25 16.97%
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2027
4.56 27.14%
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2028
3.36 26.34%
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2029
2.48 26.04%
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Current Ionis Pharmaceuticals, Inc. Upgrades & Downgrades

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Analyst Rating Action Date
HC Wainwright & Co.
Locked
Locked
Locked May 20 2025
Guggenheim
Locked
Locked
Locked May 01 2025
HC Wainwright & Co.
Locked
Locked
Locked May 01 2025
Needham
Locked
Locked
Locked Apr 30 2025
Needham
Locked
Locked
Locked Apr 15 2025
Needham
Locked
Locked
Locked Apr 08 2025
HC Wainwright & Co.
Locked
Locked
Locked Apr 07 2025
Analyst Rating Date
Locked
HC Wainwright & Co.:
Locked
Locked
May 20 2025
Locked
Guggenheim:
Locked
Locked
May 01 2025
Locked
HC Wainwright & Co.:
Locked
Locked
May 01 2025
Locked
Needham:
Locked
Locked
Apr 30 2025
Locked
Needham:
Locked
Locked
Apr 15 2025
Locked
Needham:
Locked
Locked
Apr 08 2025
Locked
HC Wainwright & Co.:
Locked
Locked
Apr 07 2025

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