$32.70
4.29% today
Nasdaq, Feb 28, 08:17 pm CET
ISIN
US4622221004
Symbol
IONS
Sector
Industry

Ionis Pharmaceuticals, Inc. Target price 2025 - Analyst rating & recommendation

Ionis Pharmaceuticals, Inc. Classifications & Recommendation:

Buy
68%
Hold
28%
Sell
4%

Ionis Pharmaceuticals, Inc. Price Target

Target Price $58.23
Price $31.35
Potential
Number of Estimates 22
22 Analysts have issued a price target Ionis Pharmaceuticals, Inc. 2026 . The average Ionis Pharmaceuticals, Inc. target price is $58.23. This is higher than the current stock price. The highest price target is , the lowest is .
A rating was issued by 25 analysts: 17 Analysts recommend Ionis Pharmaceuticals, Inc. to buy, 7 to hold and 1 to sell.
Analysts don't have a crystal ball either, but they do represent the opinion of the market quite well. You should not take the price potential and the ratings as a recommendation to act. Rather, they serve as an additional building block for your own opinion or stock analysis.
Analyst Estimates: Analysts believe that the Ionis Pharmaceuticals, Inc. stock has an average upside potential 2026 of . Most analysts recommend the Ionis Pharmaceuticals, Inc. stock at Purchase.

Sales and Margin forecast 2025, 2026 to 2029

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Quarter Annually
Dec '24 2025
Estimates
Revenue Million $ 705.14 657.72
10.48% 6.72%
EBITDA Margin -64.26% -90.79%
52.80% 41.30%
Net Margin -68.08% -92.92%
32.65% 36.49%

21 Analysts have issued a sales forecast Ionis Pharmaceuticals, Inc. 2025 . The average Ionis Pharmaceuticals, Inc. sales estimate is

$658m
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. This is
6.78% lower
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than the revenue of the last 12 months(TTM). The highest sales forecast is
$801m 13.53%
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, the lowest is
$475m 32.72%
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.

This results in the following potential growth metrics:

Revenue Estimates

2024 $705m 10.48%
2025
$658m 6.72%
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2026
$871m 32.40%
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2027
$1.2b 37.02%
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2028
$1.7b 43.54%
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2029
$2.3b 35.61%
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7 Analysts have issued an Ionis Pharmaceuticals, Inc. EBITDA forecast 2025. The average Ionis Pharmaceuticals, Inc. EBITDA estimate is

$-597m
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. This is
32.03% lower
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than the EBITDA of the last 12 months(TTM). The highest EBITDA forecast is
$-496m 9.73%
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, the lowest is
$-717m 58.49%
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.

This results in the following potential growth metrics and future EBITDA Margins:

EBITDA Estimates

2024 $-453m 36.79%
2025
$-597m 31.79%
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2026
$-439m 26.48%
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2027
$-206m 52.96%
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EBITDA Margin

2024 -64.26% 52.80%
2025
-90.79% 41.30%
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2026
-50.41% 44.48%
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2027
-17.30% 65.68%
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18 Ionis Pharmaceuticals, Inc. Analysts have issued a net profit forecast 2025. The average Ionis Pharmaceuticals, Inc. net profit estimate is

$-611m
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. This is
27.31% lower
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than the net profit for the last 12 months(TTM). The highest net profit forecast is
$-441m 8.22%
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, the lowest is
$-794m 65.46%
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.

This results in the following potential growth metrics and future Net Margins:

Net Profit Estimates

2024 $-480m 18.75%
2025
$-611m 27.31%
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2026
$-488m 20.18%
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2027
$-228m 53.29%
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2028
$81.8m 135.88%
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2029
$489m 498.46%
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Net Margin

2024 -68.08% 32.65%
2025
-92.92% 36.49%
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2026
-56.02% 39.71%
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2027
-19.10% 65.91%
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2028
4.77% 124.97%
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2029
21.07% 341.72%
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Earnings per share, P/E ratio and EV/sales Estimates 2025, 2026 to 2029

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Quarter Annually
Dec '24 2025
Estimates
Earnings Per Share $ -3.04 -3.87
18.75% 27.30%
P/E negative
EV/Sales 7.05

18 Analysts have issued a Ionis Pharmaceuticals, Inc. forecast for earnings per share. The average Ionis Pharmaceuticals, Inc. <a href=https://blog.stocksguide.com/knowledge/eps-simply-explained>EPS is

$-3.87
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. This is
27.30% lower
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than earnings per share in the financial year 2024. The highest <a href=https://blog.stocksguide.com/knowledge/eps-simply-explained>EPS forecast is
$-2.79 8.22%
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, the lowest is
$-5.03 65.46%
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.

This results in the following potential growth metrics and future valuations:

Earnings Per Share

2024 $-3.04 18.75%
2025
$-3.87 27.30%
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2026
$-3.09 20.16%
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2027
$-1.44 53.40%
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2028
$0.52 136.11%
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2029
$3.10 496.15%
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P/E ratio

Current -10.32 41.79%
2025
-8.10 21.51%
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2026
-10.15 25.31%
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2027
-21.73 114.09%
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2028
60.55 378.65%
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2029
10.12 83.29%
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Based on analysts' sales estimates for 2025, the Ionis Pharmaceuticals, Inc. stock is valued at an <a href=https://blog.stocksguide.com/knowledge/enterprise-value-sales-simply-explained>EV/Sales of

and an <a href=https://blog.stocksguide.com/knowledge/price-sales-ratio-simply-explained>P/S ratio of .

This results in the following potential growth metrics and future valuations:

EV/Sales

Current 6.58 16.92%
2025
7.05 7.20%
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2026
5.33 24.47%
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2027
3.89 27.02%
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2028
2.71 30.33%
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2029
2.00 26.26%
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P/S ratio

Current 7.06 15.80%
2025
7.58 7.27%
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2026
5.72 24.47%
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2027
4.18 27.02%
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2028
2.91 30.33%
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2029
2.15 26.26%
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Current Ionis Pharmaceuticals, Inc. Upgrades & Downgrades Beta

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Analyst Rating Action Date
BMO Capital Locked ➜ Locked Locked Feb 20 2025
Citigroup Locked ➜ Locked Locked Feb 20 2025
RBC Capital Locked ➜ Locked Locked Feb 20 2025
Needham Locked ➜ Locked Locked Feb 20 2025
RBC Capital Locked ➜ Locked Locked Jan 15 2025
Needham Locked ➜ Locked Locked Dec 20 2024
Piper Sandler Locked ➜ Locked Locked Nov 14 2024
Analyst Rating Date
Locked
BMO Capital: Locked ➜ Locked
Feb 20 2025
Locked
Citigroup: Locked ➜ Locked
Feb 20 2025
Locked
RBC Capital: Locked ➜ Locked
Feb 20 2025
Locked
Needham: Locked ➜ Locked
Feb 20 2025
Locked
RBC Capital: Locked ➜ Locked
Jan 15 2025
Locked
Needham: Locked ➜ Locked
Dec 20 2024
Locked
Piper Sandler: Locked ➜ Locked
Nov 14 2024

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