$4.45
10.70% yesterday
Nasdaq, Aug 13, 10:00 pm CET
ISIN
US48576U1060
Symbol
KPTI

Karyopharm Therapeutics, Inc. Target price 2025 - Analyst rating & recommendation

Karyopharm Therapeutics, Inc. Classifications & Recommendation:

Buy
77%
Hold
23%

Karyopharm Therapeutics, Inc. Price Target

Target Price $15.30
Price $4.45
Potential
Number of Estimates 7
7 Analysts have issued a price target Karyopharm Therapeutics, Inc. 2026 . The average Karyopharm Therapeutics, Inc. target price is $15.30. This is higher than the current stock price. The highest price target is , the lowest is .
A rating was issued by 13 analysts: 10 Analysts recommend Karyopharm Therapeutics, Inc. to buy, 3 to hold and 0 to sell.
Analysts don't have a crystal ball either, but they do represent the opinion of the market quite well. You should not take the price potential and the ratings as a recommendation to act. Rather, they serve as an additional building block for your own opinion or stock analysis.
Analyst Estimates: Analysts believe that the Karyopharm Therapeutics, Inc. stock has an average upside potential 2026 of . Most analysts recommend the Karyopharm Therapeutics, Inc. stock at Purchase.

Sales and Margin forecast 2025, 2026 to 2032

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Quarter Annually
Dec '24 2025
Estimates
Revenue Million $ 145.24 148.40
0.54% 2.18%
EBITDA Margin -82.00% -89.35%
7.18% 8.96%
Net Margin -52.62% -71.77%
46.31% 36.40%

9 Analysts have issued a sales forecast Karyopharm Therapeutics, Inc. 2025 . The average Karyopharm Therapeutics, Inc. sales estimate is

$148m
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. This is
4.41% higher
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than the revenue of the last 12 months(TTM). The highest sales forecast is
$159m 11.93%
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, the lowest is
$133m 6.23%
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.

This results in the following potential growth metrics:

Revenue Estimates

2024 $145m 0.54%
2025
$148m 2.18%
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2026
$165m 11.28%
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2027
$219m 32.32%
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2028
$388m 77.42%
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2029
$435m 12.18%
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2030
$544m 25.18%
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2031
$638m 17.17%
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2032
$677m 6.19%
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3 Analysts have issued an Karyopharm Therapeutics, Inc. EBITDA forecast 2025. The average Karyopharm Therapeutics, Inc. EBITDA estimate is

$-133m
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. This is
79.41% lower
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than the EBITDA of the last 12 months(TTM). The highest EBITDA forecast is
$-137m 84.68%
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, the lowest is
$-127m 72.37%
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.

This results in the following potential growth metrics and future EBITDA Margins:

EBITDA Estimates

2024 $-119m 7.68%
2025
$-133m 11.34%
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EBITDA Margin

2024 -82.00% 7.18%
2025
-89.35% 8.96%
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9 Karyopharm Therapeutics, Inc. Analysts have issued a net profit forecast 2025. The average Karyopharm Therapeutics, Inc. net profit estimate is

$-107m
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. This is
70.36% lower
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than the net profit for the last 12 months(TTM). The highest net profit forecast is
$-66.0m 5.50%
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, the lowest is
$-141m 124.87%
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.

This results in the following potential growth metrics and future Net Margins:

Net Profit Estimates

2024 $-76.4m 46.60%
2025
$-107m 39.37%
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2026
$-65.7m 38.30%
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2027
$-39.3m 40.17%
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2028
$-18.9m 51.98%
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2029
$5.1m 126.85%
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2030
$19.1m 277.51%
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2031
$30.9m 61.65%
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2032
$36.5m 18.10%
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Net Margin

2024 -52.62% 46.31%
2025
-71.77% 36.40%
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2026
-39.80% 44.55%
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2027
-18.00% 54.77%
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2028
-4.87% 72.94%
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2029
1.17% 124.02%
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2030
3.52% 200.85%
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2031
4.85% 37.78%
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2032
5.39% 11.13%
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Earnings per share, P/E ratio and EV/sales Estimates 2025, 2026 to 2032

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Quarter Annually
Dec '24 2025
Estimates
Earnings Per Share $ -9.41 -12.43
49.92% 32.09%
P/E negative
EV/Sales 1.47

9 Analysts have issued a Karyopharm Therapeutics, Inc. forecast for earnings per share. The average Karyopharm Therapeutics, Inc. EPS is

$-12.43
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. This is
68.43% lower
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than earnings per share in the financial year 2024. The highest EPS forecast is
$-7.70 4.34%
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, the lowest is
$-16.41 122.36%
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.

This results in the following potential growth metrics and future valuations:

Earnings Per Share

2024 $-9.41 49.92%
2025
$-12.43 32.09%
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2026
$-7.67 38.29%
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2027
$-4.59 40.16%
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2028
$-2.20 52.07%
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2029
$0.59 126.82%
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2030
$2.23 277.97%
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2031
$3.61 61.88%
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2032
$4.26 18.01%
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P/E ratio

Current -0.54 60.86%
2025
-0.32 41.25%
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2026
-0.52 62.50%
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2027
-0.88 69.23%
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2028
-1.82 106.82%
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2029
6.80 473.63%
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2030
1.80 73.53%
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2031
1.11 38.33%
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2032
0.94 15.32%
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Based on analysts' sales estimates for 2025, the Karyopharm Therapeutics, Inc. stock is valued at an EV/Sales of

and an P/S ratio of .

This results in the following potential growth metrics and future valuations:

EV/Sales

Current 1.53 4.08%
2025
1.47 4.17%
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2026
1.32 10.14%
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2027
1.00 24.43%
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2028
0.56 43.64%
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2029
0.50 10.85%
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2030
0.40 20.11%
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2031
0.34 14.66%
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2032
0.32 5.80%
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P/S ratio

Current 0.24 64.75%
2025
0.23 4.26%
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2026
0.21 10.13%
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2027
0.16 24.44%
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2028
0.09 43.61%
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2029
0.08 10.83%
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2030
0.06 20.15%
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2031
0.05 14.58%
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2032
0.05 5.87%
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Current Karyopharm Therapeutics, Inc. Upgrades & Downgrades

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Analyst Rating Action Date
Baird
Locked
Locked
Locked Aug 12 2025
HC Wainwright & Co.
Locked
Locked
Locked Jul 16 2025
Baird
Locked
Locked
Locked May 13 2025
Barclays
Locked
Locked
Locked May 13 2025
RBC Capital
Locked
Locked
Locked May 13 2025
Baird
Locked
Locked
Locked Mar 03 2025
HC Wainwright & Co.
Locked
Locked
Locked Feb 26 2025
Analyst Rating Date
Locked
Baird:
Locked
Locked
Aug 12 2025
Locked
HC Wainwright & Co.:
Locked
Locked
Jul 16 2025
Locked
Baird:
Locked
Locked
May 13 2025
Locked
Barclays:
Locked
Locked
May 13 2025
Locked
RBC Capital:
Locked
Locked
May 13 2025
Locked
Baird:
Locked
Locked
Mar 03 2025
Locked
HC Wainwright & Co.:
Locked
Locked
Feb 26 2025

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