$37.71
0.89%
Nasdaq, Oct 02, 04:00 pm EDT. Closed.
ISIN
US81734D1046
Symbol
SEPN

Septerna Target price 2026 - Analyst rating & recommendation

Septerna Classifications & Recommendation

Buy
94%
Hold
6%

Septerna Price Target

Target Price $56.10
Price $37.71
Potential
Number of Estimates 11
11 Analysts have issued a price target Septerna 2027 . The average Septerna target price is $56.10. This is higher than the current stock price. The highest price target is , the lowest is .
A rating was issued by 16 analysts: 15 Analysts recommend Septerna to buy, 1 to hold and 0 to sell.
Analysts don't have a crystal ball either, but they do represent the opinion of the market quite well. You should not take the price potential and the ratings as a recommendation to act. Rather, they serve as an additional building block for your own opinion or stock analysis.
Analyst Estimates: Analysts believe that the Septerna stock has an average upside potential 2027 of . Most analysts recommend the Septerna stock at Purchase.

Sales and Margin forecast 2026, 2027 to 2033

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Select at least one metric to display the chart.


Quarter Annually
Dec '25 2026
Estimates
Revenue Million $ 45.95 97.97
4,154.63% 113.20%
EBITDA Margin -172.34% -76.01%
97.66% 55.90%
Net Margin -106.38% -64.19%
98.40% 39.66%

12 Analysts have issued a sales forecast Septerna 2026 . The average Septerna sales estimate is

$98.0m
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. This is
0.93% lower
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than the revenue of the last 12 months(TTM). The highest sales forecast is
$124m 25.30%
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, the lowest is
$52.2m 47.17%
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.

This results in the following potential growth metrics:

Revenue Estimates

2025 $46.0m 4,154.63%
2026
$98.0m 113.20%
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2027
$83.4m 14.83%
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2028
$68.3m 18.09%
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2029
$45.5m 33.38%
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2030
$85.6m 88.05%
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2031
$194m 126.41%
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2032
$313m 61.71%
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2033
$680m 116.85%
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3 Analysts have issued an Septerna EBITDA forecast 2026. The average Septerna EBITDA estimate is

$-74.5m
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. This is
77.71% lower
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than the EBITDA of the last 12 months(TTM). The highest EBITDA forecast is
$-76.7m 82.94%
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, the lowest is
$-71.5m 70.74%
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.

This results in the following potential growth metrics and future EBITDA Margins:

EBITDA Estimates

2025 $-79.2m 0.29%
2026
$-74.5m 5.97%
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2027
$-132m 76.71%
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2028
$-160m 21.71%
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EBITDA Margin

2025 -172.34% 97.66%
2026
-76.01% 55.90%
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2027
-157.70% 107.47%
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2028
-234.33% 48.59%
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12 Septerna Analysts have issued a net profit forecast 2026. The average Septerna net profit estimate is

$-62.9m
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. This is
159.45% lower
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than the net profit for the last 12 months(TTM). The highest net profit forecast is
$-40.3m 66.17%
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, the lowest is
$-107m 339.44%
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.

This results in the following potential growth metrics and future Net Margins:

Net Profit Estimates

2025 $-48.9m 31.92%
2026
$-62.9m 28.66%
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2027
$-106m 68.88%
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2028
$-137m 29.27%
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2029
$-147m 7.21%
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2030
$-154m 4.44%
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2031
$-143m 6.97%
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2032
$-156m 8.80%
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2033
$-150m 3.59%
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Net Margin

2025 -106.38% 98.40%
2026
-64.19% 39.66%
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2027
-127.30% 98.32%
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2028
-200.91% 57.82%
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2029
-323.34% 60.94%
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2030
-179.56% 44.47%
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2031
-73.78% 58.91%
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2032
-49.64% 32.72%
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2033
-22.07% 55.54%
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Earnings per share, P/E ratio and EV/sales Estimates 2026, 2027 to 2033

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Select at least one metric to display the chart.


Quarter Annually
Dec '25 2026
Estimates
Earnings Per Share $ -1.10 -1.38
84.85% 25.45%
P/E negative
EV/Sales 14.17

12 Analysts have issued a Septerna forecast for earnings per share. The average Septerna EPS is

$-1.38
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. This is
155.56% lower
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than earnings per share in the financial year 2025. The highest EPS forecast is
$-0.88 62.96%
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, the lowest is
$-2.33 331.48%
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.

This results in the following potential growth metrics and future valuations:

Earnings Per Share

2025 $-1.10 84.85%
2026
$-1.38 25.45%
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2027
$-2.33 68.84%
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2028
$-3.01 29.18%
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2029
$-3.22 6.98%
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2030
$-3.37 4.66%
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2031
$-3.13 7.12%
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2032
$-3.41 8.95%
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2033
$-3.28 3.81%
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P/E ratio

Current -69.83 692.38%
2026
-27.39 60.78%
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2027
-16.22 40.78%
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2028
-12.54 22.69%
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2029
-11.70 6.70%
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2030
-11.20 4.27%
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2031
-12.04 7.50%
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2032
-11.07 8.06%
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2033
-11.48 3.70%
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Based on analysts' sales estimates for 2026, the Septerna stock is valued at an EV/Sales of

14.17
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and an P/S ratio of
17.97
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.

This results in the following potential growth metrics and future valuations:

EV/Sales

Current 14.04
2026
14.17 0.90%
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2027
16.63 17.41%
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2028
20.31 22.09%
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2029
30.49 50.11%
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2030
16.21 46.82%
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2031
7.16 55.83%
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2032
4.43 38.16%
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2033
2.04 53.89%
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P/S ratio

Current 17.80 98.33%
2026
17.97 0.93%
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2027
21.10 17.41%
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2028
25.76 22.09%
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2029
38.66 50.11%
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2030
20.56 46.82%
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2031
9.08 55.83%
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2032
5.62 38.16%
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2033
2.59 53.89%
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Current Septerna Upgrades & Downgrades

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Analyst Rating Action Date
JP Morgan
Locked
➜
Locked
Locked Aug 19 2026
Jones Trading
Locked
➜
Locked
Locked Aug 13 2026
HC Wainwright & Co.
Locked
➜
Locked
Locked Aug 12 2026
Wells Fargo
Locked
➜
Locked
Locked Aug 12 2026
Guggenheim
Locked
➜
Locked
Locked Aug 11 2026
HC Wainwright & Co.
Locked
➜
Locked
Locked Jul 01 2026
Guggenheim
Locked
➜
Locked
Locked Jul 01 2026
Analyst Rating Date
Locked
JP Morgan:
Locked
➜
Locked
Aug 19 2026
Locked
Jones Trading:
Locked
➜
Locked
Aug 13 2026
Locked
HC Wainwright & Co.:
Locked
➜
Locked
Aug 12 2026
Locked
Wells Fargo:
Locked
➜
Locked
Aug 12 2026
Locked
Guggenheim:
Locked
➜
Locked
Aug 11 2026
Locked
HC Wainwright & Co.:
Locked
➜
Locked
Jul 01 2026
Locked
Guggenheim:
Locked
➜
Locked
Jul 01 2026

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