$17.63
0.62% day before yesterday
Nasdaq, Aug 22, 10:00 pm CET
ISIN
US91678A1079
Symbol
UPB

Upstream Bio Target price 2025 - Analyst rating & recommendation

Upstream Bio Classifications & Recommendation:

Buy
88%
Hold
13%

Upstream Bio Price Target

Target Price $76.50
Price $17.63
Potential
Number of Estimates 3
3 Analysts have issued a price target Upstream Bio 2026 . The average Upstream Bio target price is $76.50. This is higher than the current stock price. The highest price target is , the lowest is .
A rating was issued by 8 analysts: 7 Analysts recommend Upstream Bio to buy, 1 to hold and 0 to sell.
Analysts don't have a crystal ball either, but they do represent the opinion of the market quite well. You should not take the price potential and the ratings as a recommendation to act. Rather, they serve as an additional building block for your own opinion or stock analysis.
Analyst Estimates: Analysts believe that the Upstream Bio stock has an average upside potential 2026 of . Most analysts recommend the Upstream Bio stock at Purchase.

Sales and Margin forecast 2025, 2026 & 2027

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Quarter Annually
Dec '24 2025
Estimates
Revenue Million $ 2.37 1.75
0.42% 26.20%
EBITDA Margin -3,277.64% -8,662.09%
94.78% 164.28%
Net Margin -3,223.63% -7,976.72%
100.53% 147.45%

5 Analysts have issued a sales forecast Upstream Bio 2025 . The average Upstream Bio sales estimate is

$1.7m
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. This is
35.70% lower
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than the revenue of the last 12 months(TTM). The highest sales forecast is
$3.1m 14.15%
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, the lowest is
$559k 79.46%
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.

This results in the following potential growth metrics:

Revenue Estimates

2024 $2.4m 0.42%
2025
$1.7m 26.20%
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2026
$1.4m 21.73%
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2027
$1.6m 13.44%
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2 Analysts have issued an Upstream Bio EBITDA forecast 2025. The average Upstream Bio EBITDA estimate is

$-152m
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. This is
24.77% lower
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than the EBITDA of the last 12 months(TTM). The highest EBITDA forecast is
$-158m 29.72%
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, the lowest is
$-147m 21.07%
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.

This results in the following potential growth metrics and future EBITDA Margins:

EBITDA Estimates

2024 $-77.7m 93.96%
2025
$-152m 95.03%
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2026
$-173m 14.00%
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2027
$-203m 17.54%
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EBITDA Margin

2024 -3,277.64% 94.78%
2025
-8,662.09% 164.28%
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2026
-12,615.78% 45.64%
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2027
-13,072.12% 3.62%
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5 Upstream Bio Analysts have issued a net profit forecast 2025. The average Upstream Bio net profit estimate is

$-140m
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. This is
26.76% lower
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than the net profit for the last 12 months(TTM). The highest net profit forecast is
$-138m 25.03%
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, the lowest is
$-142m 28.83%
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.

This results in the following potential growth metrics and future Net Margins:

Net Profit Estimates

2024 $-76.4m 99.69%
2025
$-140m 82.60%
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2026
$-159m 13.73%
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2027
$-145m 8.39%
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Net Margin

2024 -3,223.63% 100.53%
2025
-7,976.72% 147.45%
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2026
-11,589.99% 45.30%
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2027
-9,359.57% 19.24%
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Earnings per share, P/E ratio and EV/sales Estimates 2025, 2026 & 2027

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Quarter Annually
Dec '24 2025
Estimates
Earnings Per Share $ -1.49 -2.59
98.67% 73.83%
P/E negative
EV/Sales 318.38

5 Analysts have issued a Upstream Bio forecast for earnings per share. The average Upstream Bio EPS is

$-2.59
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. This is
26.96% lower
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than earnings per share in the financial year 2024. The highest EPS forecast is
$-2.64 29.41%
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, the lowest is
$-2.56 25.49%
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.

This results in the following potential growth metrics and future valuations:

Earnings Per Share

2024 $-1.49 98.67%
2025
$-2.59 73.83%
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2026
$-2.95 13.90%
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2027
$-2.70 8.47%
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P/E ratio

Current
2025
-6.80 21.32%
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2026
-5.98 12.06%
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2027
-6.53 9.20%
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Based on analysts' sales estimates for 2025, the Upstream Bio stock is valued at an EV/Sales of

318.38
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and an P/S ratio of
543.41
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.

This results in the following potential growth metrics and future valuations:

EV/Sales

Current 204.72
2025
318.38 55.52%
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2026
406.75 27.76%
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2027
358.56 11.85%
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P/S ratio

Current
2025
543.41 55.52%
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2026
694.24 27.76%
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2027
611.99 11.85%
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Current Upstream Bio Upgrades & Downgrades

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Analyst Rating Action Date
JP Morgan
Locked
Locked
Locked Nov 05 2024
Piper Sandler
Locked
Locked
Locked Nov 05 2024
TD Cowen
Locked
Locked
Locked Nov 05 2024
William Blair
Locked
Locked
Locked Nov 05 2024
Analyst Rating Date
Locked
JP Morgan:
Locked
Locked
Nov 05 2024
Locked
Piper Sandler:
Locked
Locked
Nov 05 2024
Locked
TD Cowen:
Locked
Locked
Nov 05 2024
Locked
William Blair:
Locked
Locked
Nov 05 2024

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