$24.53
5.10% day before yesterday
Nasdaq, Nov 14, 10:00 pm CET
ISIN
US91678A1079
Symbol
UPB

Upstream Bio Target price 2025 - Analyst rating & recommendation

Upstream Bio Classifications & Recommendation:

Buy
89%
Hold
11%

Upstream Bio Price Target

Target Price $62.22
Price $24.53
Potential
Number of Estimates 4
4 Analysts have issued a price target Upstream Bio 2026 . The average Upstream Bio target price is $62.22. This is higher than the current stock price. The highest price target is , the lowest is .
A rating was issued by 9 analysts: 8 Analysts recommend Upstream Bio to buy, 1 to hold and 0 to sell.
Analysts don't have a crystal ball either, but they do represent the opinion of the market quite well. You should not take the price potential and the ratings as a recommendation to act. Rather, they serve as an additional building block for your own opinion or stock analysis.
Analyst Estimates: Analysts believe that the Upstream Bio stock has an average upside potential 2026 of . Most analysts recommend the Upstream Bio stock at Purchase.

Sales and Margin forecast 2025, 2026 to 2032

Create a premium account to unlock analyst estimates. Learn more

Quarter Annually
Dec '24 2025
Estimates
Revenue Million $ 2.37 2.47
0.42% 4.14%
EBITDA Margin -3,277.64% -6,506.89%
94.78% 98.52%
Net Margin -3,223.63% -6,240.72%
100.53% 93.59%

6 Analysts have issued a sales forecast Upstream Bio 2025 . The average Upstream Bio sales estimate is

$2.5m
Unlock
. This is
11.86% lower
Unlock
than the revenue of the last 12 months(TTM). The highest sales forecast is
$3.7m 32.00%
Unlock
, the lowest is
$1.5m 47.50%
Unlock
.

This results in the following potential growth metrics:

Revenue Estimates

2024 $2.4m 0.42%
2025
$2.5m 4.14%
Unlock
2026
$1.2m 50.16%
Unlock
2027
$891k 27.54%
Unlock
2028
$5.9m 561.28%
Unlock
2029
$15.1m 155.51%
Unlock
2030
$125m 730.41%
Unlock
2031
$275m 119.72%
Unlock
2032
$528m 92.10%
Unlock

2 Analysts have issued an Upstream Bio EBITDA forecast 2025. The average Upstream Bio EBITDA estimate is

$-161m
Unlock
. This is
14.44% lower
Unlock
than the EBITDA of the last 12 months(TTM). The highest EBITDA forecast is
$-167m 18.97%
Unlock
, the lowest is
$-156m 11.04%
Unlock
.

This results in the following potential growth metrics and future EBITDA Margins:

EBITDA Estimates

2024 $-77.7m 93.96%
2025
$-161m 106.73%
Unlock
2026
$-185m 15.09%
Unlock
2027
$-201m 8.74%
Unlock

EBITDA Margin

2024 -3,277.64% 94.78%
2025
-6,506.89% 98.52%
Unlock
2026
-15,026.83% 130.94%
Unlock
2027
-22,549.58% 50.06%
Unlock

6 Upstream Bio Analysts have issued a net profit forecast 2025. The average Upstream Bio net profit estimate is

$-154m
Unlock
. This is
25.45% lower
Unlock
than the net profit for the last 12 months(TTM). The highest net profit forecast is
$-147m 20.08%
Unlock
, the lowest is
$-157m 28.02%
Unlock
.

This results in the following potential growth metrics and future Net Margins:

Net Profit Estimates

2024 $-76.4m 99.69%
2025
$-154m 101.60%
Unlock
2026
$-179m 15.93%
Unlock
2027
$-207m 15.92%
Unlock

Net Margin

2024 -3,223.63% 100.53%
2025
-6,240.72% 93.59%
Unlock
2026
-14,517.40% 132.62%
Unlock
2027
-23,221.53% 59.96%
Unlock

Earnings per share, P/E ratio and EV/sales Estimates 2025, 2026 to 2032

Create a premium account to unlock analyst estimates. Learn more

Quarter Annually
Dec '24 2025
Estimates
Earnings Per Share $ -1.49 -2.85
98.67% 91.28%
P/E negative
EV/Sales 386.20

6 Analysts have issued a Upstream Bio forecast for earnings per share. The average Upstream Bio EPS is

$-2.85
Unlock
. This is
25.55% lower
Unlock
than earnings per share in the financial year 2024. The highest EPS forecast is
$-2.73 20.26%
Unlock
, the lowest is
$-2.91 28.19%
Unlock
.

This results in the following potential growth metrics and future valuations:

Earnings Per Share

2024 $-1.49 98.67%
2025
$-2.85 91.28%
Unlock
2026
$-3.31 16.14%
Unlock
2027
$-3.83 15.71%
Unlock

P/E ratio

Current -10.81 43.86%
2025
-8.60 20.42%
Unlock
2026
-7.42 13.72%
Unlock
2027
-6.40 13.75%
Unlock

Based on analysts' sales estimates for 2025, the Upstream Bio stock is valued at an EV/Sales of

386.20
Unlock
and an P/S ratio of
537.10
Unlock
.

This results in the following potential growth metrics and future valuations:

EV/Sales

Current 340.41 36.38%
2025
386.20 13.45%
Unlock
2026
774.91 100.65%
Unlock
2027
1,069.35 38.00%
Unlock
2028
161.71 84.88%
Unlock
2029
63.29 60.86%
Unlock
2030
7.62 87.96%
Unlock
2031
3.47 54.49%
Unlock
2032
1.81 47.94%
Unlock

P/S ratio

Current 473.42 25.44%
2025
537.10 13.45%
Unlock
2026
1,077.70 100.65%
Unlock
2027
1,487.19 38.00%
Unlock
2028
224.90 84.88%
Unlock
2029
88.02 60.86%
Unlock
2030
10.60 87.96%
Unlock
2031
4.82 54.49%
Unlock
2032
2.51 47.94%
Unlock

Current Upstream Bio Upgrades & Downgrades

Create a Premium account to unlock Upgrades/Downgrades. Learn more
Analyst Rating Action Date
Truist Securities
Locked
Locked
Locked Oct 14 2025
JP Morgan
Locked
Locked
Locked Nov 05 2024
Piper Sandler
Locked
Locked
Locked Nov 05 2024
TD Cowen
Locked
Locked
Locked Nov 05 2024
William Blair
Locked
Locked
Locked Nov 05 2024
Analyst Rating Date
Locked
Truist Securities:
Locked
Locked
Oct 14 2025
Locked
JP Morgan:
Locked
Locked
Nov 05 2024
Locked
Piper Sandler:
Locked
Locked
Nov 05 2024
Locked
TD Cowen:
Locked
Locked
Nov 05 2024
Locked
William Blair:
Locked
Locked
Nov 05 2024

Register for Free

StocksGuide is the ultimate tool for easily finding, analyzing and tracking stocks. Learn from successful investors and make informed investment decisions. We empower you to become a confident, independent investor.

The Apple stock at a glance with charts, current key metrics, news and stock analyses.
The Best Dividend Stocks in the Dividend Top Scorer list.
Stock Analyses of the Best Stocks Worldwide.
Start building wealth today